Hossein Ardeschir Ghofrani Selected Research

Fibronectins (Fibronectin)

4/2012	PAR-2 inhibition reverses experimental pulmonary hypertension.
11/2009	Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.

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Hossein Ardeschir Ghofrani Research Topics

Disease

51	Pulmonary Hypertension 01/2023 - 04/2002
25	Pulmonary Arterial Hypertension 10/2022 - 04/2002
19	Hypoxia (Hypoxemia) 01/2022 - 01/2006
18	Vascular Remodeling 02/2021 - 04/2004
9	Fibrosis (Cirrhosis) 04/2024 - 09/2002
7	Familial Primary Pulmonary Hypertension 10/2022 - 07/2005
7	Cardiomegaly (Heart Hypertrophy) 10/2016 - 04/2004
6	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2022 - 11/2009
6	Heart Diseases (Heart Disease) 01/2022 - 09/2005
5	Lung Diseases (Lung Disease) 10/2022 - 11/2009
4	Hypertrophy 01/2018 - 08/2007
3	Cardiovascular Diseases (Cardiovascular Disease) 06/2023 - 01/2012
3	Pulmonary Heart Disease (Cor Pulmonale) 01/2022 - 04/2004
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 03/2014
3	Right Ventricular Hypertrophy 01/2020 - 01/2010
3	Idiopathic Pulmonary Fibrosis 01/2017 - 06/2011
3	Heart Failure 08/2016 - 01/2015
3	Neoplasms (Cancer) 01/2010 - 06/2007
2	Ischemia 06/2023 - 01/2017
2	Ventricular Tachycardia 06/2023 - 01/2023
2	Hypotension (Low Blood Pressure) 01/2021 - 04/2006
2	Emphysema 01/2019 - 01/2015
2	Body Weight (Weight, Body) 12/2018 - 06/2012
2	Lung Neoplasms (Lung Cancer) 11/2017 - 11/2009
2	Vascular Diseases (Vascular Disease) 11/2015 - 10/2005
1	Pulmonary Embolism 04/2024
1	Lung Injury 04/2024
1	Inflammation (Inflammations) 04/2024
1	Hyperemia 02/2024
1	Coronary Artery Disease (Coronary Atherosclerosis) 06/2023
1	Tachycardia (Tachyarrhythmias) 06/2023
1	Myocardial Ischemia (Ischemic Heart Diseases) 06/2023
1	Multiple Sclerosis 05/2023
1	Long QT Syndrome 05/2023
1	Coronary Disease (Coronary Heart Disease) 01/2023
1	Ventricular Premature Complexes (Premature Ventricular Contraction) 01/2023
1	End Stage Liver Disease 01/2023
1	Atrial Premature Complexes (Premature Atrial Contraction) 01/2023

Drug/Important Bio-Agent (IBA)

15	MonocrotalineIBA 02/2021 - 04/2004
10	Sildenafil Citrate (Viagra)FDA Link 01/2018 - 04/2002
9	Iloprost (Ventavis)FDA Link 05/2010 - 04/2002
8	Soluble Guanylyl CyclaseIBA 01/2020 - 01/2006
7	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2015 - 04/2004
6	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2021 - 04/2002
6	riociguatIBA 01/2021 - 04/2011
6	Phosphodiesterase 5 InhibitorsIBA 01/2020 - 06/2005
5	Bleomycin (Blenoxane)FDA LinkGeneric 04/2024 - 06/2011
5	Oxygen (Dioxygen)IBA 06/2023 - 01/2006
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2015
5	Semaxinib (SU5416)IBA 01/2021 - 01/2012
4	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2021 - 06/2005
4	Vasodilator Agents (Vasodilators)IBA 03/2020 - 04/2002
4	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 09/2013
4	CollagenIBA 11/2015 - 11/2009
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 06/2012
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2005
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 12/2018 - 01/2012
3	EndotoxinsIBA 01/2017 - 04/2006
3	Chymases (Chymase)IBA 10/2015 - 01/2013
3	ProstaglandinsIBA 12/2012 - 07/2005
3	Imatinib Mesylate (Gleevec)FDA Link 06/2012 - 10/2005
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2012 - 09/2002
3	tolafentrineIBA 03/2011 - 04/2004
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2023 - 10/2022
2	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 03/2022 - 01/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2018 - 11/2015
2	CytokinesIBA 11/2017 - 11/2009
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017 - 11/2009
2	TRPC6 Cation ChannelIBA 01/2017 - 12/2006
2	Tadalafil (Cialis)FDA Link 01/2015 - 08/2012
2	Small Interfering RNA (siRNA)IBA 09/2013 - 04/2011
2	Platelet-Derived Growth FactorIBA 06/2012 - 04/2012
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 06/2012 - 10/2005
2	Fibronectins (Fibronectin)IBA 04/2012 - 11/2009
2	diethylstilbestrol monophosphate (PDES)IBA 04/2011 - 01/2010
2	Protein Isoforms (Isoforms)IBA 01/2010 - 11/2009
2	Phosphodiesterase InhibitorsIBA 01/2010 - 07/2005
2	Vasoconstrictor AgentsIBA 10/2007 - 04/2006
2	ThromboxanesIBA 01/2006 - 07/2005
2	15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidIBA 01/2006 - 07/2005
1	salicylhydroxamic acid (SHAM)IBA 02/2024
1	Indicators and Reagents (Reagents)IBA 06/2023
1	Troponin IIBA 06/2023
1	EnzymesIBA 06/2023
1	Cortisone FDA Link 05/2023
1	Polyvinyl Chloride (PVC)IBA 01/2023
1	SodiumIBA 01/2023
1	Vitamin K FDA Link 01/2023
1	Carbon MonoxideIBA 10/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	jugloneIBA 01/2022
1	Alanine Transaminase (SGPT)IBA 01/2022
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 01/2022
1	4-S-(propionic acid)sulfidocyclophosphamide (PASP)IBA 01/2022
1	GoldIBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	TransferasesIBA 01/2022

Therapy/Procedure

21	Therapeutics 05/2023 - 04/2002
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2010
1	Thrombectomy 04/2024